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Herpes simplex virus variants resistant to high concentrations of acyclovir exist in clinical isolates? Expression of the gene of interest in these progeny can be modulated using a substituted tetracycline compound? The research team found that infections developed in the uninfected partner in only 4 of the 743 couples in which the infected partner took Valtrex, whereas 16 of 741 uninfected partners developed the infection when placebo was taken!
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